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The compound binds the growth-hormone-releasing-hormone receptor on somatotrophs, mimicking endogenous GHRH and triggering an adenylyl-cyclase / cAMP / protein-kinase-A signalling cascade
They have vitamins A and C and a flavone called apigenin
But individual responses vary, and monitoring is appropriate
Ongoing investigations in our laboratory and clinical program aim to further substantiate this surprising observation in MDS and in clonal hematopoiesis of indeterminate significance (CHIP) and in clarifying the mechanism behind these effects. Further analysis of prospective cohorts with serial biospecimens would be advantageous to understand the potential connection between GLP-1 exposure and inflammasone markers and how this could influence ROS and DNA damage
This is in addition to other crazy things going on, such as me getting sinus surgery (without any pain meds), a hurricane hitting, and watching my New York Jets take a beating
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